glp-1 weight loss treatments List of approved and pending medications Long-term Success of GLP-1s Hinges
Description
Guzman CB, Zhang XM, Liu R, Regev A, Shankar S, Garhyan P, et al
doi:10.2165/00003088-199325020-00003 213
doi: 10.1073/pnas.0706890104 60 EkstrandBYoungJFRasmussenMK
According to recent data, only about 9% of individuals aged 65 and older have used GLP-1 drugs, with a mere 1% utilizing them solely for weight loss
Enhanced agonist residence time, internalization rate and signalling of the GIP receptor variant [E354Q] facilitate receptor desensitization and long-term impairment of the GIP system
Medical weight loss should be supervised, personalized, and focused on long-term metabolic health, not just the number on the scale
