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Enrollees underwent random allocation in a 2:1:1:1:1:2:2 distribution to receive weekly subcutaneous retatrutide at doses of 1, 4 mg (starting dose 2 mg), 4 mg (starting dose 4 mg), 8 mg (starting dose 2 mg), 8 mg (starting dose 4 mg), or vs

Discounting the trials that did not show benefit for MI, this reduction ranged from 12% for liraglutide in the LEADER trial [54] up to 25% for albiglutide in the HARMONY OUTCOMES trial [56]

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Tsou SH, Luo KS, Huang CN, et al

The SELECT trial is designed to fill the gap of randomized trial evidence on cardiovascular outcomes with treatment of overweight or obesity independent of the effect that semaglutide has on diabetes, says Dr