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GLP-1 directly stimulates POMC/CART neurons and indirectly inhibits neuropeptide Y (NPY) and agouti-related peptide (AgRP) to increase measures of satiety and decrease hunger [32]

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The treatment benefit on the primary composite endpoint was not evident in patients taking SGLT2 inhibitors at baseline, but there were few events in these patients

Independent Licensed Clinicians are healthcare professionals who review health information, determine whether GLP-1 medication is appropriate, and write prescriptions when clinically warranted
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