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Additionally, because many people with diabetes or who are overweight may control their condition with diet, other medications and therapies, or choose to not seek treatment, not all people who meet these clinical criteria would use GLP-1 drugs
10 Experts have also raised cost-effectiveness concerns for NASH treatments, citing questions around long-term efficacy, side effects and net healthcare system costs
This model works well when payer reimbursement exceeds acquisition cost

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Rather than stimulating insulin production, as sulfonylureas do, TZDs act peripherally
