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Human islets used for IHC were washed in PBS after 24 hours of liraglutide or saline treatment and then fixed in 10% neutral buffered formalin overnight at 4C

That hormone binds to receptors on certain cells, triggering the body to suppress glucagon, release insulin, and slow digestion

A 2023 analysis in Obesity Reviews emphasized that incretin-based therapies produce the most durable outcomes when patients pursue structured medical weight loss programs rather than viewing medication as a standalone solution

doi:10.1016/j.pharmthera.2012.07.006 18

It is investigational and is being studied in Eli Lilly's Phase 3 TRIUMPH (obesity-focused) and TRANSCEND-T2D (type 2 diabetes) programs
