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A1C reduction with Rybelsus (oral semaglutide) In one clinical study, people taking oral semaglutide daily lowered their A1C (a blood sugar test) by 1.2% over 26 weeks

Comparative outcome tables would assist, but data still accumulates

GLP-1 medications are not appropriate for all patients

There is only limited data on the role of specific bacterial species on incretins

When initiating OZEMPIC, consider reducing the dose of concomitantly administered insulin secretagogue (such as sulfonylureas) or insulin to reduce the risk of hypoglycemia [see Warnings and Precautions (5.5), Adverse Reactions (6)]