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The first GLP-1RAs Exenatide synthesized by exendin-4 was approved by the FDA in 2005 (Mariam and Niazi, 2024)

Source: Phase 2 trial data (Jastreboff et al., NEJM 2023)

We're really starting to dramatically improve outcomes for people with diabetes and kidney disease

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It releases the thyroid hormone, which helps regulate metabolism, development, and temperature
