astria therapeutics glp-1 receptor agonist weight management diabetes treatments Agonists Linked to Reduced Asthma Exacerbations in Overweight and Obese Adults Without How the GLP-1 receptor agonist

T2DM, type 2 diabetes mellitus

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Randomized controlled trials in youth with obesity (age 18 years) that assessed anthropometric and metabolic parameters were included

Adverse Effects and Long-Term Safety Concerns While GLP-1 receptor agonists have shown significant benefits, their widespread use is limited by potential side effects such as gastrointestinal distress, pancreatitis risk, and concerns over long-term metabolic effects

Although currently FDA-approved for diabetes and weight management, clinical evidence indicates these medications also interact with the brains neurological reward pathways involved in substance use disorder

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