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The etiology of HIT is primarily related to genetic polymorphisms of DAO or HNMT, diseases associated with DAO or HNMT deficiency, dysbacteriosis, drugs that inhibit DAO activity, foods rich in histamine, foods that inhibit DAO, and foods that promote histamine release

The full gastrointestinal picture is more telling

[DOI] [PubMed] [Google Scholar] 75.Scott HA, Gibson PG, Garg ML, Pretto JJ, Morgan PJ, Callister R, Wood LG

1999 Aug 20;379(1):19-31

This includes ongoing clinician support, 24/7 messaging, side effect monitoring, personalized medication adjustment, educational resources, and 1-to-1 coaching from nurses

STUDIES on GLP-1: Two double blinded randomized controlled trials showed GLP-1 agonsits improved the apnea-hypopnea index (AHI), INDEPENDENT of whether there was weight loss