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Specific circumstances requiring urgent consultation include: if you develop severe abdominal pain, fever, persistent vomiting, blood in your stools, or significant changes in bowel habits whilst taking weight loss medication

Beyond the pancreas, the GIP receptor (GIPR) is expressed within the pericytes and mesothelial cells of the adipose tissue (Campbell et al

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GLP-1Rs agonists exert neuro-humoral actions by stimulating insulin secretion and suppressing glucagon release in a glucose-dependent manner, delaying gastric emptying, and reducing appetite via central nervous system pathways