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Month-over-month ADM prescribing increased in October, decreased in November, and increased again in December 2025

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Sin embargo, dos estudios aleatorizados, doble ciego, que incluyeron 16.492 pacientes y 5.380 pacientes con DM2, el Saxagliptin Assessment of Vascular Outcomes Reported (SAVOR)70 y el Examitation of Cardiovascular Outcomes with Alogliptin versus standar of care (EXAMINE)71, reportaron tasas bajas de pancreatitis aguda similares a los grupos placebo (EXAMINE, 22 y 16 pacientes) y (SAVOR, 12 y 8 pacientes)

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If GLP-1 therapy is initiated , a structured monitoring plan should include: Regular assessment of weight, BMI and nutritional status Monitoring of hydration and renal function, particularly if experiencing significant gastrointestinal symptoms For diabetes patients, appropriate retinopathy surveillance if glycaemic control improves rapidly (especially with semaglutide) [5] [11] Regular review of Crohn's disease activity using clinical and biochemical markers Remember that you are an active participant in your healthcare decisions, and your concerns and experiences should guide the treatment plan

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