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Conclusion: This meta-analysis of RCTs provides reassuring evidence that GLP-1 receptor agonists were not associated with an increased risk of gastrointestinal cancers, with signals suggesting a possible reduction in colorectal and liver cancer incidence that should be interpreted cautiously

Enteroendocrine cells-sensory sentinels of the intestinal environment and orchestrators of mucosal immunity

There are a couple of reasons for that

In that study, semaglutide treatment improved cardiac mitophagy to suppress the activation of the NLRP3 inflammasome (36)

We now understand that T2DM is characterised by elevated fasting glucagon levels (50), while glucose suppression following a glucose challenge is stunted (51)

Combining these effects during active infection makes it harder to distinguish medication side effects from illness symptoms, complicates hydration status monitoring, and may prevent adequate caloric intake needed for immune function