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A new clinical trial showed promising results in curbing alcohol cravings in individuals with moderate alcohol-use disorder

These effects were observed with central, but not peripheral, administration of the agonist and antagonist, suggesting receptor expression on the luminal, CSF-facing side of the choroid plexus, which aligned with GLP-1R-mediated modulation of luminally-expressed transporters in excised choroid plexus

GLP-1 receptor agonists may aid smoking cessation by curbing cravings and mitigating weight gain, which often are impediments in quitting, according to a presentation at the American Psychiatric Association Annual Meeting