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The Role of GLP-1 in Appetite Regulation The first major player is a hormone called glucagon-like peptide-1 (GLP-1)

However, those with existing gallstones need extra vigilance, particularly during the first 20 weeks when risk may be higher based on trial observations

Always use FDA-approved sites: abdomen, thigh, or upper arm, and consult your healthcare provider if you have concerns about proper technique

This steady glucose response encourages ongoing GLP-1 release in your gut, complementing your medication and keeping you feeling full longer

The most common experience during week 1 includes: Mild-to-moderate nausea, especially after eating Reduced appetite and an earlier feeling of fullness Possible fatigue or low energy as calorie intake drops Mild headache, often linked to reduced food and fluid intake The starting dose for Ozempic is 0.25 mg weekly