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Furthermore, changes in blood pressure or heart rate may reveal the bodys response to fluid depletion

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The EPIC-PEP trial also spanned the period of Delta and then Omicron variant prevalence

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In agreement with recent clinical studies suggesting that pharmacological agonism of GLP-1Rs may be an effective therapeutic strategy to treat secondary lymphedema in these groups of patients, using murine models, this study demonstrated that GLP-1Rs are expressed in the lymphatic vasculature and are specifically enriched in the lymphatic endothelium