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Since being overweight or obese greatly increases the likelihood of developing colorectal cancer (CRC) [148]

Funding This work was supported by grants from the National Natural Science Foundation of China (U21A20364) and National Key Research and Development Project of China (2024YFC3308400)

However, instead of feeling the burst of energy you expected from losing weight, you feel like you are walking through sand

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Furthermore, exogenous administration of glucagon was shown early on to inhibit food intake in humans and rodents (62, 63)

Whether this distinct property of saxagliptin could interact with pathways of bone metabolism and bone turnover, thus having a relatively negative impact on bone mass or strength, needs to be elucidated
