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Many laboratories prepare single-use aliquots to minimize this risk

Despite the different doses of semaglutide and tirzepatide and timepoints studied, the results of SURMOUNT-5 and the Truveta Research study were consistent, namely that tirzepatide-based medications performed better than semaglutide-based medications: SURMOUNT-5 study : At 72 weeks, weight loss was 20.2% for Zepbound (tirzepatide AOM) compared to 13.7% for Wegovy (semaglutide AOM)

Why this matters for Canada: While this pricing is US-only, the move tells us something important

Waste and Environmental Impact: Chemical peptide synthesis is inherently solvent-intensive

You can dispose of both with other medical waste, but the needle part is sharp

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