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Emerging physiological and clinical evidence suggests that testosterone plays a central role in skeletal muscle anabolism through pathways involving muscle protein synthesis, satellite cell activation, and androgen receptor-mediated transcriptional signaling

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These precedents highlight the need for indication-specific risk assessment and careful differentiation between mechanism-based toxicity and species-specific artifacts

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"We don't know if there's a benefit, or if there's increased risk, if you get to pregnancy at a lower weight and then come off the medication," said study first author Dr
