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DA5-CH, a novel GLP-1/GIP dual agonist, effectively ameliorates the cognitive impairments and pathology in the APP/PS1 mouse model of alzheimers disease

changes in various parameters from baseline to week 104 and week 52

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Chronic hypercortisolism causes more persistent visceral adiposity than HFD-induced obesity

17 35 Therefore, careful clinical monitoring is warranted, especially during the early phases of treatment

Dose escalation protocols are standard practice, with typical progression to .25mg increments over monthly intervals