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As insulin levels normalize and drop from previously elevated states, IGF-1 levels may also decline

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One practical, 2 to 3 liters (8 to 12 cups) of fluid daily , mainly water, adjusted for your body size and medical conditions

Supplementary information Acknowledgements We acknowledge the contributions of the clinical staff of the Intramural Research Program of the National Institute on Drug Abuse, and the Clinical Research Unit of Johns Hopkins Bayview Medical Center, as well as the University of Maryland, Baltimore, a member of the Graduate Partnership Program, National Institutes of Health (NIH)