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Whether these effects are also due to CNS activation is unclear but they do seem to be independent of the effect of chronic GLP-1 administration to reduce body weight

Exendin-4 Protects Pancreatic Beta Cells From Palmitate-Induced Apoptosis by Interfering With GPR40 and the MKK4/7 Stress Kinase Signalling Pathway

doi: 10.3390/nu14224886

[DOI] [PMC free article] [PubMed] [Google Scholar] 67.Mitchell JL, Lyons HS, Walker JK, Yiangou A, Grech O, Alimajstorovic Z, et al

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This dual approach ensures a comprehensive treatment strategy, ideal for those with limited success with traditional medical weight loss methods like diet and exercise