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for severe obesity and Type 2 diabetes, the entry of low-cost generic versions has led to widespread misuse via online pharmacies and wellness clinics.

While weight loss effects can vary depending on the drug, studies show that all GLP-1 meds can result in an average weight loss of about 10.5 to 15.8 []

Teva Pharmaceuticals has launched the first generic GLP-1 drug for weight loss in adults and adolescents
The magnitude of the benefits of GLP-1RA and SGLT-2 inhibitors on MACE are similar, ranging from 12 to 14% reduction of risk, but only GLP-1RA may reduce the risk of stroke

A large global retrospective cohort study (n=331,863 matched patients

Two major ongoing trials are likely to change that, with potentially big implications for clinical practice.
