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Why Side Effects Happen (Slow Gastric Emptying) Have you wondered why GLP-1 medications cause gastrointestinal side effects in the treatment of type 2 diabetes

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These medications are synthetic analogs or mimetics of human GLP-1 that resist degradation by the enzyme dipeptidyl peptidase-4 (DPP-4), allowing for prolonged therapeutic action

People in the studies were overweight (BMI 27-29.9 kg/m2) or obese (BMI greater than or equal to 30 kg/m2) before taking Saxenda

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Subsequently, glucose exits into the bloodstream via the facilitated glucose transporter 2 on the basolateral membrane