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Based on this, we synthesized a panel of exendin-4 analogs with single amino acid substitutions close to the N-terminus, which we hypothesized could modulate receptor trafficking and/or signaling (Supplementary Fig

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In the GLP-1 context, transfers occur in several scenarios: Lab to new plant: For example, when Lillys new Indiana plant begins making tirzepatide, the established R&D process (including fermentor operating procedures or peptide coupling protocols) must be painstakingly transferred

Wadden TA, Chao AM, Machineni S, et al

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