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The dual incretin agonist tirzepatide reduced 24-hour ambulatory BP for adults with obesity-related hypertension, with the effects potentially independent of weight loss, according to data from a planned substudy of the SURMOUNT-1 trial.“Tirzepatide led to clinically meaningful reductions in ambulatory blood pressure among adults with overweight and obesity, with reductions in the range

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The once-daily pill significantly reduced A1C (1.3-1.6%) and led to an average 16-pound weight loss
