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GLP-1, produced in enteroendocrine L-cells and preproglucagon neurons in the NTS, plays a central coordinating role by integrating peripheral and central signals, then modulating downstream pathways that control appetite, metabolism, and behavior [9,34]

Higher doses also showed more problems

By intention to treat analysis (n=8, 12 months), at 3, 6 and 12 months compared to baseline, weight loss was 6.8 4.1 kg, 10.0 5.6 kg and 8.9 8.4 kg (p=0.026)

10.1016/s2213-8587(21)00179-0

Do GLP-1 drugs increase SCFAs or diversity

This typically includes your current weight, height (to calculate your Body Mass Index or BMI), and any diagnosed health conditions that are related to your weight, such as diabetes, high blood pressure, or sleep apnea