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GLP-1: Limited Driven by nervous system dysregulation: disrupted feeding cycles, altered stress responses, and changes in the neurological architecture governing hunger, satiety, and reward
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[7] [8] Some patients report experiencing mood changes, irritability, or emotional fluctuations whilst using these treatments
Clinical trials demonstrate that patients treated with Zepbound experience modest but meaningful blood pressure reductions alongside substantial weight loss
In recent studies, TH-expressing neurons in the ARH, coexpressing neither neuropeptide Y (NPY)/agouti-related peptide (AgRP) nor CART, were implicated in metabolic control (29)
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