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Semaglutide works in a similar way by helping to slow down how quickly food leaves the stomach and by acting on areas of the brain involved in appetite control

In a study of more than 1,600 adults with type 2 diabetes, those who received the highest dose of orforglipron on average shed 10.5% of their weight.

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The study was led by first author Dr Sudipta Sen, associate professor, and senior author and Professor Omonele Nwokolo, both from the Department of Anesthesiology, Critical Care and Pain Medicine at McGovern Medical School at UTHealth Houston."Our findings were quite surprising