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When to Seek Medical Advice : Patients should contact their healthcare provider if they experience unexplained bone pain, height loss, or fractures with minimal trauma, as these may indicate significant bone loss requiring evaluation and intervention

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Most protocols begin at a low dose, such as 2.5 mg, once per week

C.et al (2016)

A recent post-hoc analysis of SURPASS-3 (NCT03882970) in adults with T2DM reported decreases in fat mass and muscle fat infiltration (MFI) accompanying weight loss [65], suggesting potential improvements in muscle quality that may be especially promising for older adults

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