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Hanmi Pharmaceutical has started dosing patients in a Korean phase 3 trial of efpeglenatide for type 2 diabetes, adding a second late-stage path for the GLP-1 drug after filing it as an obesity treatment

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GLP-1 functions as an immune modulator because it controls macrophage polarization and T-cell functions [12,13]
That means if you think you are injecting 0.5 mg, you might actually be getting 0.3 mg, a dose too low to produce meaningful appetite suppression or weight loss

TL;DR GLP-1 microdosing involves taking significantly lower doses of medications like semaglutide (0.05-0.25mg weekly) compared to standard therapeutic doses (0.25-2.4mg)
