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Missing injections disrupts the steady-state concentration that the medication needs to work effectively
Second, GLP-1 receptor agonists may slow gallbladder emptying

doi: 10.3233/CH-242134 56 BullFCAl-AnsariSSBiddleSBorodulinKBumanMPCardonGet al

Its also part of the impetus behind research exploring whether GLP-1 analogs could help treat conditions like addiction

3 - PMID 40934115 - Oral Semaglutide at a Dose of 25 mg in Adults with Overweight or Obesity, NEJM (2025)

The vision loss can be mild or severe, and unfortunately, it may be permanent
