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It slows the rate at which food moves from your stomach to the duodenum (the small intestine) by relaxing the stomach muscles

Reframing the Narrative Around GLP1 Skin Changes Skin responding to weight loss is not a flaw

The drug companies marketed it backwards because lose 15% of your body weight sells better than normalize your insulin signaling and reduce systemic inflammation. But it set up the wrong framework

GLP-1 receptor activation has been shown to counteract these mechanisms by reducing macrophage infiltration in adipose tissue, suppressing NF-Bmediated cytokine release, and promoting an anti-inflammatory immune profile (49)

Your ghrelin (hunger hormone) concentrations rebound, and insulin sensitivity may decline if lifestyle changes alone do not persist

This was accompanied by higher adiponectin gene expression and secretion (increasing insulin-sensitizing adipokine levels) and a sharp reduction in inflammatory cytokine TNF secretion [12,40]