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The realistic expectation is gradual metabolic support over months, not acute effects within days

Results depend on consistency and proper dosing

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Efficacy and safety of tirzepatide, GLP-1 receptor agonists, and other weight loss drugs in overweight and obesity: a network meta-analysis

GLP-1 receptor distribution and function by tissue The brain: appetite, satiety, and reward The central nervous system is where much of the modern interest in GLP-1 lives, because the brain is where appetite is controlled

One of today's most well-known metabolic signals in that network and class of popular weight loss medications is a gut hormone called GLP-1