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Liraglutide also suppressed NLRP3 transcription

Adults with overweight or obesity who took semaglutide demonstrated short- and longer-term improvements in controlling their eating habits and substantial weight loss, according to the latest findings from the Semaglutide Treatment Effect in People with obesity (STEP) 5 trial

Studies show up to 25-39% of weight lost on GLP-1s can come from lean mass - without intentional resistance training and adequate protein

Switching to the oral small molecule glucagon-like peptide-1 (GLP-1) orforglipron after taking injectable GLP-1s helped patients maintain mostbut not allof their weight loss, according to a clinical trial led by Weill Cornell Medicine and NewYork-Presbyterian investigators.