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Description
The recent data provide evidence that GLP-1R activation affects the mechanisms of signal transduction associated with insulin resistance, energy homeostasis of the brain, neurogenesis, synaptic functioning, neuroinflammation and other cell responses to stress, pathological protein aggregates, proteostasis, the cerebrovascular system, and the BBB [42]
Not accredited
It developed gradually as audiences noticed visible changes over time
However, the rapid inactivation of GLP-1 by DPP-4 in vivo limits its application in clinic
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