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No heart attacks, strokes, or cardiovascular deaths have been attributed to retatrutide in published trial data
It can bind to proteins in the blood, which allows it to provide a gentle, extended signal to the pituitary over several days
These side effects are usually mild to moderate and often improve over time
Multiple newer hormonal-based fixed combination dual or triple agonist drugs are even surpassing the currently approved medications
J Clin Endocrinol Metab 2016;101: 44e51
