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Tirzepatide's pharmacokinetic engineering builds on GLP-1 agonist acylation principles but applies them to a GIP-backbone peptide, producing a dual-receptor agonist with a 5-day half-life

M., et al., Tirzepatide Once Weekly for the Treatment of Obesity in People With Type 2 Diabetes (SURMOUNT2): A DoubleBlind, Randomised, Multicentre, PlaceboControlled, Phase 3 Trial, Lancet 402, no

They contain a blend of Methionine, Choline Chloride, Carnitine, and Dexpanthenol (Lipo-C), which work together to break down fat and enhance energy production