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Description
Activation of these receptors by GLP-1R agonists has been shown to confer protection against microvascular damage, particularly in models of diabetic retinopathy and stroke

doi:10.1111/obr.12474 172

and regulate blood lipid metabolism (56)
PattiMEHoutenSMBiancoACBernierRLarsenPRHolstJJet al
7476 Evidence suggests that PKA-dependent protection of GLP-1 is mediated through enhanced ATF4-CHOP-growth arrest and DNA damage inducible gene 34 (GADD34) signaling, resulting in eukaryotic initiation factor 2 alpha dephosphorylation and translational recovery

03.01.24 First status conference held The first status conference in the GLP-1 RA MDL was held on March 14
