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These findings highlight the need for prospective studies that integrate longitudinal assessments of weight, thyroid function, and levothyroxine dosing to validate these results and clarify the mechanisms linking GLP-1RA use to cardiovascular outcomes, including atrial fibrillation/flutter and stroke

Taken together, these results clearly demonstrate that in patients with both type 1 and type 2 diabetes, improvements in glycemic control will reduce the risk of the development and progression of DR

Common Early Tirzepatide Side Effects and Duration Nausea is the most frequently reported side effect in the first week of tirzepatide therapy, affecting approximately 25 to 35 percent of patients in clinical studies

A1C reduction ranges from 0.6% to 1.5%, depending on dose and baseline glucose levels

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Connie Yang, MD, is a dermatologist in New York City, and advisor to Dermstore, an online skincare emporium