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Much of the focus on the impact of GLP-1 receptor agonists (and combination drugs with components that target other receptors such as gastric inhibitory polypeptide collectively termed GLP-1s in this article) to date has been on their potential to improve long-term health outcomes for people with type 2 diabetes, obesity, and related cardiovascular diseases

Until recently, the most durable weight-loss intervention was bariatric surgery, which is also associated with excellent health outcomes

3 Glucagon is the hormone most people associate with raising blood sugar, but it has a second function

Conversely, a study published in the British Journal of Pharmacology discussed the neuroprotective properties of GLP-1 and associated peptide hormones, which include semaglutide