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A common approach is to start the new agent at its lowest dose, allow washout if needed, and up-titrate gradually while monitoring A1C, fasting glucose, and GI tolerance

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Source: FMI analysis, 2026

Meet the experts: Kristi Tough DeSapri, MD, is the founding physician at Bone and Body Womens Health , in Winnetka, Illinois

Emerging evidence suggests that metabolic signaling pathways, long considered peripheral to brain reward systems, may directly modulate central mechanisms underlying substance use disorders (SUDs)

Ali walks every patient through what's actually being prescribed and why during your consultation