glp 1 agonists uses GLP-1 Receptor and Research to Treat Overeating and Substance Use Disorders GLP-1s for Weight Loss: What

Schmidt PT, Hartmann B, Bregenholt S et al (2000) Deficiency of the intestinal growth factor, glucagon-like peptide 2, in the colon of SCID mice with inflammatory bowel disease induced by transplantation of CD4+ T cells

Cost per unit of weight loss Beyond efficacy, cost efficiency matters for researchers planning sustained protocols

Common DPP-4 Inhibitors: Sitagliptin (Januvia Merck) Saxagliptin (Onglyza AstraZeneca) Linagliptin (Tradjenta Boehringer Ingelheim / Lilly) Alogliptin (Nesina Takeda) In contrast: DPP-4 inhibitors work by prolonging the life of native GLP-1

PMID: 12609761

When Should You Consider a GLP-1 Agonist

Back Finan, B, Ma, T, Ottaway, M (20 Oct 2013) 'Unimolecular dual incretins maximize metabolic benefits in rodents, monkeys, and humans', Science Translational Medicine , 5/209, 2-9a151