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Other authors declared they had no relevant financial interests

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Dietary and Lifestyle Strategies to Support Safe Semaglutide Use Patients using semaglutide with diverticulitis history should prioritize soft, easily digestible foods during the initial weeks of treatment and gradually reintroduce whole grains and high-fiber foods as tolerated

The cardiovascular and disease-modifying benefits seen in the 2025 studies typically emerge over months to a year of consistent use

13 , 14 These differences may in part reflect the distinct mechanisms through which GLP-1 RAs act on both central appetite regulation and peripheral metabolic pathways, which we have discussed in detail in a previous review

7 For Heartburn/Reflux: Avoiding personal trigger foods (often spicy, fatty, acidic, caffeine, chocolate, peppermint) is important