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Cardiovascular outcome trials, including the LEADER and SUSTAIN-6 studies, demonstrated that GLP-1 agonists reduce major adverse cardiac events in high-risk populations

The current label includes once-daily tablets and injection presentations

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Patients also report improved mood and energy, partly because fragmented sleep no longer suppresses restorative REM and deep sleep stages

Gastroparesis Exacerbation by a GLP-1 Agonist. Journal of the Endocrine Society, vol

This gap between what doctors recommend and what insurance companies approve is a huge hurdle
