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Guidelines recommend GLP-1 medications with proven cardiovascular benefit for diabetic patients with or at high risk for cardiovascular disease

Exendin-4 activates the cAMP/CREB signaling pathway, thereby inhibiting cell proliferation and promoting apoptosis

Recent evidence suggests that their pleiotropic effectsbeyond glycemic control and weight lossinclude anti-inflammatory, immunomodulatory, and antioxidative effects, which may beneficially support various dermatologic conditions such as psoriasis, hidradenitis suppurativa, acanthosis nigricans, and Hailey-Hailey disease

The increases in beta-hydroxybutyrate (78-181%) confirmed that the fatty acid oxidation mechanism was driving these changes at the cellular level

If you are considering berberine, especially if you take prescription medications or have diabetes, kidney disease, liver disease, cardiovascular disease, or are pregnant or breastfeeding, discuss it with your clinician first

Novo Nordisk is developing a new obesity drug that clinical trials suggest rivals Zepbound in effectiveness, and Eli Lilly is testing a drug that could end up being even more effective than the current products on the market