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Only 10%15% of active GLP-1 reaches the general circulation intact, thus leading to minimal fasting plasma levels of 015 pmol/L [24]

Effects of Glucagon-Like Peptide-1 Receptor Agonist Exendin-4 on the Reinstatement of Cocaine-Mediated Conditioned Place Preference in Mice

In the second study, significant increases in psychiatric conditions were noted to occur associated with GLP-1 agonist potency and total exposure in a population selected for obesity treatment

EClinicalMedicine, 88, 103464

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