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This peptide has been implicated in modulating neuronal cell differentiation, neurite outgrowth, and performing neuroprotective functions through the activation of GLP-1 receptors (GLP-1Rs), class B sub-group G protein-coupled receptors [2, 6]
10.1038/nrendo.2016.221 51 RaoR
The short half-life means drug accumulation from a double dose can cause severe GI side effects
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Average weight loss appears greater with retatrutide in early studies, but individual response depends heavily on genetics and baseline metabolic function
