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In particular, GLP-1R agonists, which have been approved by the FDA for the treatment of T2DM, are recently emerging as promising therapeutic agents in PD, increasing the expectations for identifying new PD drugs that could possibly be neuroprotective or even halt or reverse disease progression

Mechanism: This effect is mediated by the activation of the vagus nerve and direct effects on gastric smooth muscle (Zheng et al., 2024)

Exclusion Criteria Studies that did not explicitly study GLP-1-RAs or their therapeutic uses were excluded

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