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82,83 Animal studies have demonstrated the protective effects of DPP4 inhibitors in IBD

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This model is also satisfying from an evolutionary biology perspective in which GLP-1 and GIP do not have redundant functions in the brain, but rather fit into complimentary niches

Energy Economics During GLP-1 Weight Loss Muscle tissue is metabolically expensive to maintain

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50 Gastrointestinal Motility Disorders: Gastric and Intestinal Manifestations GLP-1 RAs reduce GI motility and prolong intestinal transit time, effects that have raised concerns regarding an increased risk of gastroparesis, intestinal obstruction, or ileus
