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Since tirzepatide may slow gastric emptying as part of its mechanism of action, patients with pre-existing severe gastroparesis could experience worsening of symptoms, including nausea, vomiting, and potential complications related to delayed gastric emptying

Traditional GLP-1 receptor agonists, such as semaglutide, primarily promote weight loss by suppressing appetite, slowing gastric emptying, and improving insulin secretion

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That said, if you prefer plant-based proteins, its worth looking closer at the label

Taken together, current evidence supports three balanced conclusions

If your primary objective is breaking a lifelong cycle of weight gain and achieving a level of weight loss that dramatically improves your overall metabolic health, a GLP-1 is almost certainly the more potent and targeted therapy